VEGF in various forms of chronic polypoid rhinosinusitis
Keywords:
chronic polypoid rhinosinusitis, morphological study, immunohistochemical study, VEGFAbstract
The purpose of this study was to investigate VEGF in immunohistochemistry of various forms of chronic polypoid rhinosinusitis. We studied 45 patients with chronic polypoid rhinosinusitis in 2013 year, which were performed surgery followed by morphological and immunohistochemical studies of macropreparations. The study showed that polyps of patients with "neutrophilic" polypoid rhinosinusitis had greater activation of VEGF than in polyps of patients with "eosinophilic" polypoid rhinosinusitis.
References
Allergic Rhinitis and its impact on asthma update (ARIA 2008). The Belgian perspective /Bachert C. [et al.]//. B-ENT. 2008;4(4):253-257.
Eosinophil degranulation patterns in nasal polyposis: an ultrastructural study /M. Armengot L. [et al.]// Am. J. Rhinol Allergy. -Sep.-Oct. 2009. Vol.23(5). - P.466-470.
EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. //Fokkens W.J. [et al.]// Rhinology. 2012 Mar; Vol.50 (1).
Expression, localization, and significance of vascular permeability/vascular endothelial growth factor in nasal polyps. /Gosepath J. [et al.]// Am J Rhinol 2005;19:7–13.
Djuraev J. A. et al. Distribution of Allel Variants and Genotypes of Il4, Il10, Il12b, Tlr2 Genes in the Group of Patients with CPRS //Annals of the Romanian Society for Cell Biology. – 2021. – С. 4466-4470.
Djuraev J. A. et al. & Shaumarov, AZ (2021). Distribution of Allel Variants and Genotypes of Il4, Il10, Il12b, Tlr2 Genes in the Group of Patients with CPRS //Annals of the Romanian Society for Cell Biology. – С. 4466-4470.
Relationship between clinical measures and histopathologic findings in chronic rhinosinusitis. /Soler Z.M. [et al.]// Otolaryngol Head Neck Surg, 2009; Vol. 141:454-461.
The role of cytokine in eosinophilic infiltration into nasal polips /Y. Korono// International Consensus on Nasal Polyposis, Update 2006, Российская ринология – 2006 – №2 – C.31.
Vascular endothelial growth factor and children featuring nasal polyps. /Hu K.H. [et al.]// Int J Pediatr Otorhinolaryngol 2007;71:23–28.
Vascular endothelial growth factor in nasal polyps: a comparison of asthmatic and non-asthmatic patients. /Bateman N.D. [et al.]// Clin Otolaryngol Allied Sci 2004;29:677–681.
Khasanov U. S. et al. Results of frequency analysis distribution of A1188C RS3212227 polymorphism in the IL 12B gene among patients with chronic rhinosinusitis polyposis //Oriental Journal of Medicine and Pharmacology. – 2022. – Т. 2. – №. 01. – С. 104-115.
Vokhidov U. N., Nuriddinov K. N. Some modern features of the distribution and treatment of chronic polyposis rhinosinusitis //Oriental Journal of Medicine and Pharmacology. – 2022. – Т. 2. – №. 01. – С. 131-143.
Vokhidov U. N., Khasanov U. S. Immunohistochemical study of mesenchymal formations of chronic polypoid rhinosinusitis //Oriental Journal of Medicine and Pharmacology. – 2022. – Т. 2. – №. 1. – С. 144-152.
Vokhidov U. N. Prevalence of polypose process in patients with chronic polypose rhinosinusitis //International Scientific and Current Research Conferences. – 2021. – С. 106-109.
Khasanov U. S., Vokhidov U. N., Djuraev J. A. Frequency of il 12b gene polymorphism among patients with chronic rhinosinusitis polyposis. – 2022.
Vokhidov U. N., Khasanov U. S., Vokhidov N. K. The effectiveness of use macrolides in the treatment of chronic" neutrophil" polypoid rhinosinusitis //Folia Otorhinolaryngologiae et Pathologiae Respiratoriae. – 2014. – Т. 20. – №. 2. – С. 79-79.
UN V. et al. The local immunity in the tissues of various forms of nasal polyps //ALLERGY. – 111 RIVER ST, HOBOKEN 07030-5774, NJ USA : WILEY-BLACKWELL, 2016. – Т. 71. – С. 121-121.
Vokhidov U. N., Radjabov R. R. Rinoendoscopic evaluation of chronic polypoid rhinosinusitis //International Engineering Journal For Research & Development. – 2020. – Т. 5. – №. 4. – С. 5-5.
Khasanov U. S., Vokhidov U. N. Optimization of complex treatment of patients with chronic polyposis rhinosinusitis //Postgraduate doctor. – 2011. – Т. 45. – С. 501-505.