Modern view on the etiopathogenetic factors in the development of olfactory impairment in COVID-19
Keywords:
anosmia, hyposmia, new coronavirus infection, SARS-CoV-2, COVID-19Abstract
One of the symptoms of a new coronavirus infection (COVID-19) is a complete or partial violation of the sense of smell. The aim of the review was to explore the mechanisms of olfactory impairment in COVID-19. The review material included scientific publications based on the PubMed database over the past 5 years, which searched for publications on the problem of olfactory impairment in COVID-19. Publication's analysis has shown that the existing ideas about conductive anosmia are insufficient to explain the causes of olfactory impairment caused by SARS-CoV-2. The main hypothesis of olfactory impairment in COVID-19 is that anosmia/hyposmia is caused by damage not to neuronal cells (as previously assumed), but to the olfactory epithelium.
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